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KMID : 0359920100290010115
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Korean Journal of Nephrology
2010 Volume.29 No. 1 p.115 ~ p.119
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The Role of Positron-Emission Tomography in Diagnosis and Assessment of Treatment Response in Takayasu Arteritis
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Park Se-Woo
Lee Chang-Hwa
Kim Gheun-Ho
Jeong Myung-Ho
Park Soo-Yuck
Song Soon-Young
Choi Yun-Young
Kang Chong-Myung
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Abstract
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Takayasu arteritis is a nonspecific granulomatous inflammatory arteriopathy of unknown cause that results in occlusive obliteration and less commonly aneurysmal degeneration of large and medium-sized elastic arteries. The diagnosis of Takayasu arteritis and the assessment of its progression and extent remain challenging, especially in patients presenting with a constellation of non-specific symptoms and laboratory tests. The standard diagnostic procedures include biopsy, arteriography, sonography, and magnetic resonance angiography. However, these procedures are invasive or largely operator-dependent, and document only morphological changes such as stenosis, occlusion and aneurysmal transformation which mainly occur in late stages of the disease. On the other hand, Positron-emission tomography is an operator-independent, non-invasive metabolic imaging modality which plays a major role in diagnosis of nonspecific inflammatory diseases. We report a case in which Positron-emission tomography was applied to the detection of Takayasu arteritis and assessment of its disease progression.
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KEYWORD
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Takayasu arteritis, Positron-Emission Tomography, Disease progression, Diagnosis
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